Using Virtual Serial Port SDK you can create a "new" ... VB.NET and VisualBasic 6.0 are included.

Serial Communication SDK to add serial communications to your project. Communicate with a modem, scanner, printer, weight indicator or any other serial port device. The component features full com port control, binary and ASCII data transfer, RS-232 and RS-485 standards, TAPI and ISDN modem support. Used it in your ASP, ASP.NET, Visual Basic, Visual Basic .NET, Visual C++, Visual C# .NET, JavaScript and VBScript projects.