JPKD 3.0
JPKD is a computer program designed for clinical pharmacokinetic services (or TDM). It not only inherits all functionalities of mobilePK, but also has a built- in algorithm of user`s defined Bayesian model for individualized pharmacokinetic parameter estimation (UDBM) for batch input data. Users can define their own pharmacokinetic prediction models with population PK parameters and then use the defined model to solve batch prediction data or applied the defined model to therapeutic drug monitoring (TDM).
JPKD (used to be JavaPK for Desktop) not only inherits
all functionalities of mobilePK, but also include a build-in
algorithm of user`s defined Bayesian model for individualized
pharmacokinetic parameter estimation (UDBM)for batch input
data. Users can define their own model with population PK
parameters using either a single-dosed, integral equation
(for the multiple-dosed prediction) or a simple steady-state
integral equation. The user’s defined Bayesian model can also
be applied (or "save as...") for the purpose of clinical PK or
TDM. More drugs such as carbamazepine, theophylline, lithium,
immunosuppressants (tacrolimus and everolimus) and some
anti-HIV drugs (indinavir, ritonavir and enfuvirtide) have been
added for TDM application as compared to mobilePK. We also
include some examples for the user`s defined Bayesian model
(such as enoxaparin, imatinib mesylate, sirolimus and valproic
acid). JPKD is able to run on any JVM-supported desktop platform
(WinXP/NT, MacOS X, Linux-PC or any platform with Java runtime
supported).
--- PharmDatatech(c), 2004-2007
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